Sunday, September 11, 2011

Usual Interstitial Pneumonia - HRCT

HRCT of 40 Year old female showing macrocystic honeycombing, reticular
opacities predominantly in the subpleural region, architectural distortion and
areas of focal ground-glass opacity 

Mediastinal window of the same patient showing small enlarged pre tracheal lymphnode.


Idiopathic Pulmonary Fibrosis (IPF) is the most common entity of the Idiopathic Interstitial Pneumonias (IIPs). By definition, IPF is the term for the clinical syndrome associated with the morphologic pattern of UIP.
Median survival - 2 to 4 years.

Clinical features - Presents in 50 years old or older. Patients present with progressively worsening
dyspnea and nonproductive cough.

Histopathologic Features: Spatial and temporal heterogeneity, architectural distortion and fibroblastic foci.

HRCT: Distribution is apicobasal gradient and predomonently subpleural location. 
Features are macrocystic honeycombing, reticular opacities, traction bronchiectasis, architectural distortion and focal ground-glass opacity.

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