tag:blogger.com,1999:blog-8073436095132550388.post1445264996878404226..comments2023-10-26T07:33:52.930-07:00Comments on Radiodiagnosis - Imaging is Amazing-Interesting cases: Methylmalonic acidaemia (MMA)Dr.Manjunath.Y.Chttp://www.blogger.com/profile/10552212486595136424noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-8073436095132550388.post-1334989672032221692009-12-29T10:46:47.031-08:002009-12-29T10:46:47.031-08:00Thank you for your feed back , i am very much plea...Thank you for your feed back , i am very much pleased to your response . your blog is very informative ....Pramod.K.Ghttps://www.blogger.com/profile/17035883334157527259noreply@blogger.comtag:blogger.com,1999:blog-8073436095132550388.post-45954807967161838282009-12-29T09:51:13.654-08:002009-12-29T09:51:13.654-08:00Dear Dr.Pramod, HIE will have typical history and ...Dear Dr.Pramod, HIE will have typical history and clinical findings. Radiologically HIE will have elevated lactate levels and Lactate:creatinine ratio will be more than 1.5. where as Leighs syndrome will have different clinical setting and MRS will show elevated lactate levels but same is also seen in CSF unlike HIE. It is very difficult to differentiate Leighs from MMA radiologically. In our case patient had increased serum levels of methylemalanoic acid and also urine excretion. So diagnosis is most of the times by clinical/biochemical and radiological correlation.Dr.Manjunath.Y.Chttps://www.blogger.com/profile/10552212486595136424noreply@blogger.comtag:blogger.com,1999:blog-8073436095132550388.post-16862981174763188222009-12-27T23:49:50.423-08:002009-12-27T23:49:50.423-08:00In case of basal ganglia lesion with increased lac...In case of basal ganglia lesion with increased lactate in MRS , How will u differentiate with leighs syndrome and hypoxic brain injury ..... how u confirmed MMA ..Pramod.K.Ghttps://www.blogger.com/profile/17035883334157527259noreply@blogger.com